Artificial Intelligence (AI) and Remote Patient Monitoring (RPM) are transforming oncology, giving patients a greater role in managing their treatment.

Recent studies have shown that using digital tools to collect medical data outside the traditional clinical setting reduces delayed symptom reporting, limits severe side effects, decreases hospitalizations and emergency visits, while improving survival and quality of life for patients.

In practice, this means digital applications allow patients to promptly inform their doctors of any issues, reducing risks and enhancing their daily experience during treatment.

Based on these findings, in 2022, ESMO published guidelines for integrating patient-reported outcome measures (PROMs) into clinical practice, recommending electronic platforms over paper questionnaires (Ann Oncol. 2022).

Dr. Charles Ferté, Chief Medical & Patient Officer of the Resilience solution, developed in collaboration with the Institut Gustave Roussy in France, highlights that AI can address limitations in using patient reports in oncology. According to him, about 50% of patients’ side effects go unreported, either due to forgotten symptoms or staff workload. Mild but persistent side effects are often overlooked, affecting treatment effectiveness.

The Resilience solution includes an online platform for doctors and nurses to monitor symptoms and receive alerts, and a mobile app for patients to submit real-time data. Data are processed through AI algorithms and transformed into actionable insights for the oncology team, facilitating timely intervention and care optimization. This enables doctors to monitor patients in real time and prevent complications before they become serious.

Additionally, the solution incorporates Natural Language Processing (NLP) to extract data from medical notes and lab results, and a predictive algorithm estimates the risk of severe side effects and unplanned hospitalizations.

Patient engagement is crucial: compliance with weekly questionnaires reaches up to 85%, with many describing the app as a “lifeline” during treatment. Although initially thought to appeal only to younger patients, research shows acceptance spans all ages (JMIR Mhealth Uhealth. 2018; J Geriatr Oncol. 2024).

The solution can also screen large patient populations, identifying those who would benefit from a hybrid care model—digital tools combined with in-person support, such as behavioral and cognitive therapy. Continuous data collection allows RPM to expand to social and behavioral indicators, including isolation, employment, access to care, addictions, physical activity, or food insecurity.

Finally, digital data open new avenues in research: the Resilience database includes over 20,000 patients across 140 hospitals in France, Belgium, Germany, and Spain, enabling real-world data use for more targeted clinical research. In the future, digital phenotyping will allow monitoring of physical and cognitive indicators via mobile sensors like pedometers and gyroscopes, offering a more comprehensive view of the patient experience.

It is clear that cancer care can now rely not only on patient and professional engagement but also on data analysis that uncovers hidden aspects of patients’ daily lives and symptoms.

Kapa3 remains at the forefront of oncology developments, continuously updating on new technologies and practices, actively supporting patients and caregivers, and creating tools and resources that ease daily life. Focused on patient empowerment, Kapa3 bridges scientific knowledge with practical solutions, ensuring everyone feels guided and safe throughout their treatment journey.

Text/Adaptation: Ifiyenia Anastasiou for Kapa3

Sources:

Kapa3 Supports Digital Innovation for Oncology Patients at Morning Health Talks

On Thursday, 4 December 2025, the second Morning Health Talk titled “Health Data for Innovation in Greece: Building a Stronger Digital Health Ecosystem” took place at the National Documentation Centre (EKT) in Athens. The event was held in a hybrid format (in-person and online participation), bringing together health professionals, researchers, policymakers and technology partners from Greece and abroad.

During the event, international and Greek experiences were presented on the management and use of health data, digital transformation, and best practices for leveraging data to strengthen the country’s digital health ecosystem.

Among the speakers were:

  • Dr Athanasios Batagiannis, General Director, 3-psi

  • Georgios Dimitriou, Cluster Manager, Hellenic Digital Health Cluster

  • Dr Ioannis Koumpouros, Director of DigInHealth, University of West Attica

  • Elpida Fotiadou, Head of eHealth, IDIKA

With the contribution of the distinguished speakers, key issues were discussed, including infrastructure interoperability, the need for reliable data, bureaucratic barriers, gaps in digital literacy, the development of focused platforms and processes, faster care pathways and needs assessment, the reduction of information fragmentation, and the development of human-centred digital solutions with practical value and social acceptance.

KAPA3 presented its strategic approach, focusing on standardised procedures, data quality improvement, interdisciplinarity, and the use of digital tools to support people living with cancer, as well as on guidance, interaction, empowerment and patient participation in data utilisation processes. At every step, KAPA3 addresses key challenges such as data fragmentation, stakeholder collaboration and human-centred digital solutions—issues that are also summarised in the Good Practices Guide developed within the eHealth4Cancer project.

In summary, the main points highlighted were:

  • A human-centred approach and the application of good practices to ensure the usability and social acceptance of digital solutions.

  • Strengthening collaboration between healthcare professionals, researchers and citizens to develop reliable and functional digital infrastructures.

  • The need for systematic scientific research to address challenges such as skills gaps, limited access and data fragmentation.

The event provided an important opportunity for networking and knowledge exchange, promoting the alignment of digital health infrastructures with citizens’ needs and reinforcing KAPA3’s role as an active contributor to the digital transformation of healthcare in Greece.

Read the full Morning Health Talks 2025 press release here and view photos from the event.

Text/adaptation: Ifiyenia Anastasiou for Kapa3