Research Archives

Kapa3 in the second half of April: Information, collaborations and strengthening patient care

Kapa3 in April

Throughout April, Kapa3 continued to develop actions and initiatives aimed at improving access to care for oncology patients and their families, with a strong focus on information, prevention, and the development of innovative collaborations.

This period’s activities focused on raising awareness about key cancer types, improving patients’ daily lives through policy and systemic developments, and expanding partnerships that enhance the quality of care and services provided.

In an ever-evolving healthcare environment, the connection between reliable information, human support, and technology remains a key pillar for a more accessible and effective care system.

Below are the main initiatives and developments that marked the second half of the month.

Awareness

April is an awareness month for head and neck cancer as well as testicular cancer, highlighting the importance of prevention and early diagnosis. Although these types of cancer are often underrepresented in public discourse, awareness plays a crucial role in reducing late diagnoses and improving patients’ quality of life.

Patients’ rights

Important developments took place in the field of patients’ rights, including the establishment of the National Registry for Hospital-at-Home Care (NOSPI), aiming to better organise and ensure the safety of home-based care.

At the same time, the new framework for Public Administration introduces changes that directly affect citizens’ daily lives, enhancing transparency, reducing bureaucracy, and improving access to public services.

Collaborations

During April, Kapa3 further strengthened its network of collaborations through significant partnerships.

The collaboration with the PRAXI Network/FORTH, within the European smartHEALTH hub, enhances participation in innovation and health policy initiatives, opening new opportunities at European level.

In addition, the partnership with Karkinaki focuses on supporting children, adolescents, and families living with cancer, promoting a holistic approach to care.

Furthermore, the collaboration with SimasiaAI for the development of “Myrto”, an AI-powered digital assistant, highlights the importance of technology in empowering patients and improving access to reliable information and services.

Research & knowledge

A new international report on person-centred cancer care highlights the need for a holistic model that places the patient at the centre. This approach recognises not only clinical needs but also psychosocial dimensions, reinforcing the importance of patient involvement in decision-making.

Patients & society

On the occasion of European Patients’ Rights Day (18 April), Kapa3 highlighted the importance of equal access to quality care. Despite progress, challenges such as inequalities and delays remain, making the continued strengthening of support structures essential.

Supporting our work

Kapa3’s collection of handmade scarves continues to serve as a creative way of supporting the organisation’s mission, combining aesthetics with meaningful contribution to people living with cancer.

We continue to monitor developments and work towards improving patients’ daily lives — more news coming soon.

Text/adaptation: Ifigenia Anastasiou for Kapa3

Research studies giving voice to lived experience

At Kapa3, we actively encourage participation in health research studies, as we work every day alongside people affected by cancer, whether as patients or caregivers. Through this work, it becomes increasingly clear how important it is to truly listen to lived experience.

For this reason, the research initiatives we support or contribute to are not just questionnaires. They are a way to better understand the needs, experiences and priorities of the community we serve.

Through participation in these studies, individuals who are at the centre of the cancer experience are given the opportunity to share their reality. Every response, every story, every contribution adds another piece to a broader picture: a more meaningful and human-centred approach to care and support.

The contribution of each participant is highly valuable. The data collected helps us identify needs that are often not visible, better understand challenges, and design actions that reflect the real everyday lives of people.

Through participation in health research studies, lived experience can be transformed into knowledge that makes a real difference. Each study we support is part of a broader effort to understand the experiences of patients and caregivers.

Below you will find the current research studies open for participation, organised by target audience.

Each health research study includes a short description of its purpose and how participation contributes to the overall research effort.

For healthcare professionals

Patient safety culture in hospitals

A pilot study focused on the translation and adaptation of the international SOPS® Hospital Survey 2.0 developed by the AHRQ, adapted for the Greek hospital setting.

The aim of the study is to evaluate the clarity, comprehension and suitability of the tool through the participation of healthcare professionals working in hospital environments.

The study also includes a test–retest phase to assess the stability of responses over time.

Participation: https://forms.gle/Jev7mQ95vt1swtXF7

For research networks and collaborations

sleepCare – sleep quality assessment

The sleepCare research initiative, in collaboration with Christos Frantzidis (University of Lincoln) and his research team, explores sleep quality through real-life experiences and self-reported data from participants.

The aim is to better understand the factors that influence sleep in everyday life through anonymous data collection and short questionnaires.

English questionnaire: https://lnkd.in/e7wYjspX
Greek questionnaire: https://lnkd.in/ejbjGQPC
Platform: https://lnkd.in/e7YHUXdi

For breast cancer survivors

Survivorship experience and quality of life

A thesis-based research study examining fear of cancer recurrence, quality of life, and the role of social support among breast cancer survivors in Greece.

The aim is to better understand post-treatment experiences and the factors that influence psychosocial well-being.

Participation: https://docs.google.com/forms/d/e/1FAIpQLSeUgku0yi7LBGg42v_FeKtzVsj5F5uw8hYr-y-hcVKL-fhoeQ/viewform

For patients with respiratory conditions and caregivers

Lung transplantation experiences in Greece

A nationwide study collecting experiences, needs and perspectives of patients with respiratory conditions and their caregivers regarding lung transplantation.

The aim is to capture lived experience across all stages of the disease in order to improve care pathways and healthcare services.

The study is open to patients with respiratory conditions (transplanted or not) as well as their caregivers.

Participation: https://forms.gle/66h4CQJK3pdr1gKK7
Information: https://www.cysticfibrosis.gr/draseis/lung-transplant-working-group/

Text/Adaptation: Ifiyenia Anastasiou for Kapa3

Kapa3 in the First Half of March: Actions, Collaborations, and Updates for Oncology Patients

During the first half of March, Kapa3 continued to highlight important topics concerning the oncology patient support, rights, and daily lives through initiatives, collaborations, and informational activities.

Efforts focused both on strengthening access to information and services, and on promoting practical and digital tools that make patients’ daily lives easier.

In an environment where patients’ needs remain complex and constantly evolving, reliable information, enhanced collaboration among stakeholders, and the promotion of holistic care are especially important.

Below is a summary of the main developments from the month.

Collaborations

Key partnerships were strengthened with the Sarcoma Fighters Patients Association, the Hellenic Federation of Persons with Multiple Sclerosis (HFoPwMS), and Doctor Homie, aiming to enhance information, support, and quality care for patients.

Actions & Presentations

Kapa3 participated in the scientific meeting “Cancer in 2026: Challenges and Breakthroughs,” emphasizing the pivotal role of supportive care for oncology patients, while also presenting recent developments addressing their evolving needs. Kapa3 also attented the event “Facing the Challenge of Artificial Intelligence” as we remain focused on supporting dialogue around the opportunities and challenges of A.I.

Patient Rights

Supporting oncology patients remains a central goal of our initiatives. Focus was given to updates on the 2026 constant attendance allowance and improved digital access for patients to their test results.

Digital Health & Research

A new European Commission report highlights the critical role of digital health technologies in transforming healthcare systems, outlining both opportunities and challenges for the future of care.

Awareness

March is Colorectal Cancer Awareness Month, reminding everyone of the importance of prevention and early detection.

Oncology patient support remains our top priority, and we continue to monitor developments — more news will follow.

Results from the First Phase of the Knowledge Mapping of Members of the Civil Society Alliance, Greece

The first phase of the survey on the current state of knowledge and use of technological tools by members of the Civil Society Alliance, Greece, was successfully completed. Its aim was to identify the strengths, challenges, and needs of the organizations, in order to support their further development and process improvement.

The contribution of the Cancer Guidance Centre – KAPA3, particularly through the collection and analysis of data by Mr. Konstantinos Tzanas, Statistical Analyst, MSc, was significant. This involvement ensured the quality, completeness, and reliability of the results, providing a comprehensive picture of the current situation.

Key Findings

Organizations that invest in digital maturity demonstrate better financial management and overall organizational performance.
2024 inputs/budgets are the most decisive factor for organizational maturity. Medium-sized organizations (€250,000 – €600,000) show the best balance of resources and effectiveness.
Significant gaps exist in financial sustainability, particularly in revenue generation and grant acquisition, regardless of size.
Respondents’ gender does not affect evaluations, while organizational position mainly influences assessments on financial matters.

Organization Clusters

Underperforming in management – Emerging (3 organizations, 9%)
Low maturity, need to develop basic governance and financial management.
Digitally Mature Organizations (13 organizations, 39%)
High digital skills, good KPI handling, need to strengthen fundraising and strategic financing.
Organizations with Limited Resources (8 organizations, 24%)
Focus on grants, weaknesses in financial management, need for basic digital tools and KPIs.
High-Maturity Organizations (9 organizations, 27%)
Excellent governance and financial management, strong points in legal compliance and budgeting, best practices accessible for mentoring.

Strategic Recommendations

Strengthen basic governance and financial management for emerging organizations.
Leverage digital skills to enhance fundraising in digitally mature organizations.
Invest in essential financial management tools and KPIs for organizations with limited resources.
Maintain excellence and exchange best practices for high-maturity organizations.

Text/adaptation: Ifiyenia Anastasiou for Kapa3

The Impact of the Kapa3 Internship Programme: 30 Young Professionals in Our First 5 Years of Operation

The Impact of the Kapa3 Internship Programme: 30 Young Professionals in Our First 5 Years of Operation

In the five years since our establishment, thirty young people have had the opportunity to learn and grow through the Kapa3 Internship Programme.

International scientific literature highlights that internships are far more than a first work experience. They serve as a fundamental mechanism of experiential learning, enabling students to connect theoretical knowledge with real-world professional contexts.

Through their involvement in a civil society organisation like Kapa3, interns developed reflective and critical thinking skills—core elements of modern professional education. By engaging with real needs and challenges, students strengthened their professional identity and gained a deeper understanding of their role as future practitioners in health and social services. In many cases, the internship at Kapa3 played a significant role in supporting their transition from university to the labour market, enhancing their confidence, social skills, and clarity of professional direction.

Furthermore, the structured field experiences offered opportunities to build professional networks, a key factor in long-term career development.

At Kapa3, the value of internships is evident across all aspects of our work. We strive to create an environment where students can deepen their academic knowledge, apply their skills to real cases, and map out the next steps of their careers with realism and self-awareness.

The result is a community of young professionals who are both socially conscious and scientifically equipped to contribute meaningfully to health and social care. We are proud to be at the forefront of education and warmly thank our partner universities for their trust and collaboration.

KAPA3 at the ESMO Congress: Inspiration and Confirmation That We Are Moving Towards the Future

From October 17 to 20, we attended the ESMO World Congress in Berlin. The event stood out for the active participation of the Greek medical community, which led presentations on clinical data, Real-World Evidence, and up-to-date education in collaboration with the global oncology community. At the same time, Greek teams received awards in various areas (medical, nursing, institutional), inspiring us all with hope for the ongoing developments in oncology care.

Our main goal as KAPA3 was to focus on research addressing the real needs of the population within the framework of the global community. Collaborating with healthcare professionals from around the world allowed us to gather valuable knowledge and experiences. The intensive sessions and discussions broadened our understanding and prompted reflection on the next steps.

Key challenges identified for the patient advocacy community were:

Mandatory multidisciplinary assessment before starting treatment
No patient should begin treatment without undergoing a multidisciplinary assessment, including an oncology nurse, social scientist, and psychologist. This should be considered the minimum standard for all cancer patients.
Certification and quality of multidisciplinary teams
It is our duty to ensure that these teams meet quality standards. Their certification is undoubtedly complex. However, for us at KAPA3, multidisciplinary care is a fundamental criterion for service provision and must be certified. Quality care can significantly improve patient outcomes, as shown by clinical studies and research presented at this year’s congress, with potential improvements in overall survival of up to 10% (Sweden).

We are deeply proud that our work is guided by these standards precisely. In an era of remarkable progress in medicine and new therapies, we continue to strengthen the institution of research and multidisciplinary care, ensuring accessibility and patient-centered approaches aimed at quality of life.

This is the third time we have presented our efforts at an ESMO congress, in collaboration with the International University and the Nursing Department, highlighting our presence at every level. Meanwhile, trainings for other healthcare professionals take place annually within our organization in collaboration with Greek universities.

For Greek patients and their environment, we have not yet reached a point where the quality of care is considered a key objective for the entire oncology community. Our aim is to align with efforts across Europe so that, in the future, multidisciplinary assessments from the first day of diagnosis become standard practice within therapeutic protocols.

At KAPA3, we understand that quality care, inherently multidisciplinary, requires collective effort and collaboration between organizations and professionals to determine the best possible standards.

EGFR: An “Old Target” Gaining New Life in Cancer Research

When science moves forward step by step

Progress in oncology does not always come with dramatic announcements. Often, it is found in studies that show small but meaningful steps. One such case is a recent review in JAMA Oncology exploring new targeted therapies for head and neck cancer — a type of cancer often linked to smoking, alcohol consumption, or HPV infection. At Kapa3, we closely follow these developments to keep patients and their families responsibly informed,

Researchers focused on a protein called EGFR (Epidermal Growth Factor Receptor). Approximately 90% of patients with this type of cancer show overexpression of the protein, making it an attractive target for therapy. In the past, drugs such as cetuximab attempted to “block” EGFR activity, but results were limited. Patients experienced modest improvements without a significant increase in survival.

The new generation of research goes a step further. Combination therapies are being explored, such as targeting EGFR alongside immunotherapy (e.g., pembrolizumab), which strengthens the body’s defense against cancer cells. In early studies, this combination showed response rates around 45% and a median survival of approximately 18 months in patients for whom previous treatments had failed — results that, while not dramatic, are considered encouraging for this disease.

Scientists now understand that the success of targeted therapy depends on multiple factors. In many patients, cancer cells eventually develop resistance, “learning” to bypass the drug’s effect. In addition, cancers linked to HPV appear to behave differently from those that are not, opening new avenues for more personalized approaches.

Research is also focusing on identifying biomarkers — molecular indicators that can show which patients are most likely to benefit from a particular therapy. If these tools prove reliable, they could lead to more targeted, effective, and safer treatments in the future.

At the same time, newer forms of drugs are being tested, such as bispecific antibodies and antibody–drug conjugates, which aim to target cancer cells with greater precision. All of these efforts are still in early clinical trial stages, aiming to improve efficacy and reduce side effects.

The key message of this research is not that a “new drug that beats cancer” has been found, but that science continues to search, test, and learn. Every small step, every percentage of improvement, every new idea paves the way for future progress.

For people living with cancer — and their families — hope lies not only in major breakthroughs and new treatments but also in the certainty that thousands of researchers around the world are tirelessly working to make each next step a little closer to life. Because in science, as in life, progress is often measured not in leaps but in steady, human steps. At Kapa3, we are committed to sharing this news in a clear and useful way for everyone.

Read the review here

Sources:

Hwang W. et al. “Emerging EGFR-Targeted Therapy in Head and Neck Cancer: A Review.” JAMA Oncology (2025).
World Health Organization – Cancer Research Updates

Text/adaptation: Ifiyenia for Kapa3

Understanding Breast Cancer Risk Factors: What You Can and Can’t Change

October is Breast Cancer Awareness Month — a time to raise awareness, share knowledge, and remind ourselves of the importance of early detection and prevention. One of the most common questions people ask is: “What can I do to lower my risk of breast cancer?”

The truth is that while doctors don’t know exactly what causes breast cancer, research has identified certain factors that increase the likelihood of developing the disease. Some of these are beyond our control, while others are linked to lifestyle choices and can be modified. By learning the difference, we empower ourselves to take the best possible care of our health.

Unchangeable Risk Factors

Some risk factors cannot be avoided. These include:

Sex: Being female or assigned female at birth is the biggest risk factor.
Age: Risk increases with age; two out of three invasive breast cancers occur in women 55 or older.
Family History and Genetics: A family history of breast cancer or inherited genetic mutations (such as BRCA1/2) increases risk.
Personal History: Women previously diagnosed with breast cancer are more likely to develop it again.
Past Radiation: Radiation to the chest or face before age 30 raises risk.
Certain Breast Conditions: Some non-cancerous breast changes are linked to higher risk.

Lifestyle-Related Risk Factors

Our daily habits and choices also play a significant role:

Weight: Being overweight, especially after menopause, increases risk.
Physical Activity: Lack of regular exercise is linked to higher risk.
Smoking and Alcohol: Both are associated with increased breast cancer risk.
Hormonal Factors: Use of hormone replacement therapy (HRT) or hormonal contraception may raise risk in some women.
Reproductive History: Age at first childbirth, number of pregnancies, and breastfeeding history all influence risk.
Menstrual History: Early onset of menstruation is associated with slightly higher risk.

Emerging Risk Factors

Research is ongoing, but some additional factors are being studied, such as:

Low vitamin D levels.
Night-shift work and exposure to bright light at night.
Exposure to chemicals (in food, plastics, cosmetics, sunscreens, pesticides, pollution).
Frequent consumption of grilled or smoked meats.
High levels of air pollution.

Myths and Misconceptions

It’s equally important to clear up what does not increase risk. Research shows no evidence that abortion, antiperspirants, bras, or dairy products cause breast cancer.

We may not be able to control every risk factor, but every small step toward a healthier lifestyle truly makes a difference. Exercise, balanced nutrition, limiting alcohol, and avoiding smoking are not just prevention measures — they’re acts of daily self-care.
At Kapa3, we believe that awareness and support save lives. No one is ever alone on this journey. We promise to continue to speak openly, share knowledge, and stand beside every woman. Because awareness is not about fear; it’s about strength, hope, and small steps toward a healthier tomorrow.

Text/Adaptation: Ifiyenia for Kapa3

Raising the Standards: Europe’s QA Scheme for Breast Cancer Services

The European Quality Assurance (QA) Scheme for Breast Cancer Services, part of the European Commission Initiative on Breast Cancer (ECIBC), is a voluntary certification program covering the full care pathway—from screening to palliative care.

Designed to support quality improvement across Europe, it provides evidence-based guidelines and common quality and safety requirements.

The scheme has been piloted in multiple European countries, confirming its feasibility and usefulness in real healthcare settings. Services meeting the standards can apply for accredited certification, ensuring consistent, high-quality care.

The program is coordinated by the Joint Research Centre (JRC) in collaboration with DG SANTE, under Europe’s Beating Cancer Plan.

To learn more, click here

Digital poverty and social exclusion

Internet of Things in EU Households: Who is Connecting and How

A recent Eurostat article looks at how individuals across the European Union are using internet-connected devices (IoT).

In 2024, 70% of EU citizens aged 16–74 reported using Internet of Things (IoT) devices—smart technologies such as internet-connected TVs, smart speakers, fitness trackers, or doorbells. While internet-connected TVs were the most widely used device (58%), wearables like smartwatches or fitness trackers were used by 30%, and home audio systems by 19%. Less common were smart home appliances, energy management systems, security devices, health-related IoT devices, and toys.

Usage patterns vary across age groups. The youngest adults (16–24) show the highest adoption of entertainment-related IoT devices, while the 35–44 age group uses more home-related devices.

Country differences are significant: the Netherlands leads with 95% of citizens using IoT devices, while Greece ranks fourth from the last, just above Romania, Bulgaria, and Poland.

The trend towards digital inequality is concerning. Special attention is needed from social justice actors to avoid automation-driven discrimination facilitated by artificial intelligence. While digitalisation can enhance the efficiency of social protection, there is a risk it may instead serve austerity measures.