Evangeli Bista Joins the PATH Expert Group as an Independent Expert: Bringing the Patient Perspective into the New Era of AI in Cancer Care

A new contribution to the European dialogue on safe, responsible and human-centred Artificial Intelligence in healthcare

Evangeli Bista, Co-founder and Head of Operations and Development of Kapa3 – Cancer Guidance Centre, has been invited to join the Expert Group of the European research and innovation project PATH – Patient AI Treatment Hub as an independent expert.

Her participation is undertaken in a personal and independent capacity, with her professional affiliation to Kapa3 – Cancer Guidance Centre, creating an opportunity to bring into the European dialogue experience gained through direct engagement with people affected by cancer, survivors, caregivers and healthcare professionals. The PATH Terms explicitly define Expert Group members as acting independently rather than as partners, employees, agents or subcontractors of the Consortium.

What is PATH – Patient AI Treatment Hub?

PATH – Patient AI Treatment Hub is a European research and innovation project focused on supporting the safe and effective integration of Artificial Intelligence into cancer care through the development of a secure, interoperable and privacy-preserving digital platform.

The project aims to explore how Artificial Intelligence tools can be safely integrated into cancer-care pathways, supporting healthcare professionals and contributing to more personalised approaches while safeguarding privacy and health data.

At the heart of this effort lies a critical question:

How can technological innovation create meaningful value for patients while preserving trust, human oversight, safety and equity?

Participation in the PATH Expert Group

As a member of the PATH Expert Group, Evangeli Bista will contribute independent expertise, opinions, input, comments and feedback in relation to selected project use cases and activities.

The experience developed through Kapa3’s work can contribute to discussions around issues such as:

  • patient-centred cancer care,
  • patient navigation across health and social-care systems,
  • equitable access to information and services,
  • health and digital literacy,
  • health and social rights,
  • responsible use and protection of health data,
  • transparency and human oversight in Artificial Intelligence systems,
  • meaningful involvement of patients and civil society in technology design,
  • and translating technological innovation into real value for people.

Why the Patient Voice Must Be Part of Innovation

Artificial Intelligence is creating new possibilities for healthcare and cancer care. At the same time, its growing use raises important questions concerning trust, transparency, safety, equitable access and human oversight.

For Kapa3, the development of a digital solution cannot begin solely with the question of what is technologically possible.

It must also ask:

What does the patient actually need?

Can people understand the information they receive?

Do they know where that information comes from?

Can they trust the system?

Is it clear when Artificial Intelligence is being used and when human professional judgement is required?

Could digital inequalities lead to new inequalities in healthcare?

And ultimately, does innovation genuinely improve the experience and pathway of a person facing cancer?

These are questions that we believe should remain at the centre of the European discussion on Artificial Intelligence in healthcare.

Kapa3’s experience in digital health

Evangeli Bista’s participation in the PATH Expert Group comes at a time when Kapa3 is systematically expanding its work in digital health, patient navigation and the responsible use of emerging technologies to support people affected by cancer.

This broader work also includes MYRTO – Digital Navigator for Health and Social Rights, an independent Kapa3 initiative developed to help transform complex and often fragmented information on rights, benefits and administrative procedures into more accessible, structured and evidence-based guidance for patients and caregivers.

MYRTO is not part of PATH, and the two initiatives are independent from one another.

However, the experience of developing patient-facing digital services has reinforced several principles that Kapa3 considers essential:

reliable information, transparent sources, understandable communication, data protection, human oversight and a clear pathway to professional support when technology alone is not enough.

This distinction is also important from an intellectual-property perspective, since the PATH Terms preserve intellectual property that exists independently of the Expert’s Services and is not incorporated into PATH Contributions.

From information to trust

Digital transformation in healthcare is not simply about more data, more algorithms or more applications.

It is about creating greater understanding, better access and stronger trust.

For a person facing cancer, information has value when it can be translated into a meaningful next step.

Technology has value when it reduces — rather than increases — complexity.

And Artificial Intelligence has value when it strengthens, rather than replaces, human care, professional judgement and the patient’s ability to participate meaningfully in decisions affecting their life and health.

A new opportunity to contribute to the European dialogue

For Kapa3, the invitation to Evangeli Bista to participate as an independent expert in the PATH Expert Group represents an important opportunity to bring into the European dialogue experience, needs and concerns emerging from the real-world context of cancer care and patient support.

The objective remains clear:

Artificial Intelligence in healthcare should advance with safety, transparency, responsibility, equitable access and meaningful involvement of the people it is designed to serve.

Because innovation creates real value when it is designed with people and for people.


PATH – Patient AI Treatment Hub | At a glance

Field: Artificial Intelligence and data in cancer care
Project: PATH – Patient AI Treatment Hub
Focus: Safe and effective integration of AI into cancer care through secure, interoperable and privacy-preserving approaches.
Expert Group: Independent external experts providing expertise, opinions, input, comments and feedback to the Project.
Independent Expert: Evangeli Bista
Professional role: Co-founder & Head of Operations and Development
Affiliation: Kapa3 – Cancer Guidance Centre

 

“Myrto” under Scientific Evaluation: Transparency, Evidence and Human Oversight in Social Navigation for Oncology Patients

“Myrto” under Scientific Evaluation: Transparency, Evidence and Human Oversight in Social Navigation for Oncology Patients

The first closed scientific testing workshop of the Digital Health and Social Rights Navigator has been completed

Athens, 6 July 2026

The first closed scientific testing and evaluation workshop of “Myrto”, the Digital Health and Social Rights Navigator developed by the Cancer Patient Guidance Centre – Kapa3, was successfully completed.

The workshop was organised by the Cancer Patient Guidance Centre – Kapa3, with the support of René Descartes – Cnam College and the participation of SimasiaAI. It functioned as a dynamic scientific co-design workshop, bringing together specialised professionals from the fields of healthcare, social care, information technology and personal data protection.

The process was closed and strictly experimental in nature and did not constitute a public presentation of a completed product. Its purpose was to evaluate the behaviour of the application through hypothetical and fully anonymised scenarios, to record correct responses and areas requiring improvement, and to use expert feedback for the next phase of development.

The project “Myrto – Health and Social Rights Navigator” is being developed as a knowledge-based digital social navigation system, guided by the principles of explainable, transparent and human-centred Artificial Intelligence.

Its aim is to transform complex legal, administrative and social information into clear, evidence-based and practically useful guidance for oncology patients, caregivers and citizens.

“Myrto” does not replace professional social, legal, medical or clinical judgement. It operates as a supportive information and navigation tool, with clearly defined functional boundaries, human oversight and the possibility of referral to the competent services and professionals of Kapa3.

The programme is implemented with the support of the TIMA Charitable Foundation.

From Information to Understandable Knowledge

During the workshop, the need that led to the creation of “Myrto” was presented, along with the real barriers faced by patients and caregivers when seeking information on social rights, benefits and administrative procedures.

Particular emphasis was placed on addressing digital and informational exclusion. “Myrto” is designed to transform fragmented and often difficult-to-understand information into simple, structured and comprehensible guidance.

A Thematically Specialised and Curated Knowledge Base

The project’s technical partner, SimasiaAI, presented the operation of the application and the architecture used for information retrieval and synthesis.

“Myrto” uses a hybrid search mechanism that combines text retrieval and semantic search techniques, with the aim of identifying the information most relevant to the user’s question. The application operates on a thematically specialised and curated knowledge base.

A central element of its design is the traceability of information, namely the ability to link an answer to the source on which it is based. The use of validated sources reduces the risk of unsupported responses and enables the identification, review and correction of issues through a process of continuous maintenance, regular updating and adaptation to evolving guidelines and regulatory requirements.

Explainability and Human-Understandable Answers

The evaluation did not focus only on whether “Myrto” retrieves the correct information, but also on whether it can present that information in a clear, understandable and conceptually coherent way.

This approach strengthens trust, responsible use of the tool and the meaningful empowerment of citizens through a response-generation system that supports a transparent, evidence-based and human-supervised knowledge ecosystem, in which every piece of information is understandable, verifiable and connected to its source.

Data Protection and Compliance by Design

Personal data protection and regulatory compliance are embedded from the design stage of the application, in accordance with the principles of data protection by default and by design.

During the workshop, only hypothetical or fully anonymised cases were used. Particular emphasis was placed on the principles of data minimisation, anonymisation and secure processing. These principles are directly linked to contemporary requirements for the responsible development of Artificial Intelligence systems, the protection of special categories of data and compliance with the European regulatory framework.

Live Testing of Hypothetical Scenarios

The professionals who participated in the workshop tested the application individually and in small groups, using only hypothetical and fully anonymised cases. The testing was based on an approach that evaluated the behaviour of the system, examining not only whether the final answer was correct, but also whether the overall operation of the application was safe, understandable and appropriate for the specific request.

Disability Certification through KEPA

In one of the key scenarios, “Myrto” was asked to guide a hypothetical patient who did not know how to start the disability certification procedure through KEPA. The system retrieved the main steps of the process, organised the information in an understandable format and provided relevant references to the sources.

Participants evaluated:

  • the accuracy of the information,
  • the completeness of the steps,
  • the clarity of the language,
  • and the practical usefulness of the answer.

Travel from the Region for Treatment

In a second scenario, the case of an oncology patient who needed to travel from the region to another location for treatment was examined. The application identified relevant categories of socioeconomic support and benefits and presented possible next steps to the user.

The test allowed participants to assess:

  • the correct identification of the request,
  • the connection between different rights and benefits,
  • the completeness of the sources,
  • and the possibility of referral to the appropriate services.

At the same time, cases were also examined in which:

  • the question was unclear or incomplete,
  • the user did not know which right or benefit to look for,
  • clarifying questions were required,
  • medical or personalised legal advice was requested,
  • or immediate human intervention was necessary.

A Continuous Cycle of Scientific Feedback

The meeting concluded with a discussion of the testing results, a review of the technical logs and the presentation of key usage statistics for the application.

The participants’ observations are not treated as isolated comments, but as structured scientific feedback for improvement. In this way, a closed cycle of learning and feedback is created, in which technology, scientific knowledge and the experience of professionals interact continuously.

The continuous involvement of experts and the integration of structured feedback are considered critical for strengthening transparency, reliability and trust in Artificial Intelligence systems used in sensitive fields.

The Interdisciplinary Project Team

The development, scientific documentation and regulatory compliance of “Myrto” are supported by an interdisciplinary team from the fields of health services administration, information technology, personal data protection, language technology and software development. The workshop was attended by:

Evangeli Bista, Co-founder of Kapa3 and Head of Strategic Partnerships; Aristea Archontidou, Industrial Informatics Engineer with postgraduate specialisation in Health Policy and Health Services Planning; Anastasia Vlachopoulou, lawyer and member of the Thessaloniki Bar Association, specialised in personal data protection; Dimitris Papadakis, Co-founder and Sales Manager at SimasiaAI and Project Manager of the “Myrto” project; and Giannis Barous, Co-founder and CTO of SimasiaAI, PhD candidate in Computer Science based in San Francisco, who has undertaken the technical component of the project: how the system identifies the right information, how it connects it with reliable sources and how it provides answers that are evidence-based, useful and safe.

About Kapa3

The Cancer Patient Guidance Centre – Kapa3 is a social support, information and navigation organisation for oncology patients, survivors, caregivers and their families. Its aim is to contribute to equal access to oncology care, social protection and the rights associated with the cancer experience.

Every day, Kapa3 supports people who face not only the disease itself, but also a range of practical, administrative, social and psychosocial challenges. Through personalised social guidance, the organisation helps patients and caregivers learn about their rights, understand available benefits and services, navigate administrative procedures and connect with appropriate support structures.

The main pillars of Kapa3’s work include information on social and insurance rights, support in accessing health and social care services, guidance on benefits and procedures, empowerment of patients and caregivers, and connection with professionals, organisations and communities.

As part of its digital strategy, Kapa3 develops digital empowerment and social navigation tools, such as “Myrto”, the Digital Health and Social Rights Navigator. “Myrto” is designed to transform complex legal, administrative and social information into clear and evidence-based guidance for oncology patients, caregivers and citizens, always with human oversight, transparency and respect for the limits of technology.

Kapa3’s philosophy is based on the principle that care is not limited to medical treatment. It includes access to information, social protection, psychosocial support, dignity, empowerment and the ability of every person to know and claim their rights.

Through collaborations with health and social care professionals, academic and research institutions, civil society organisations, public structures, volunteers and communities, Kapa3 seeks to build bridges between the patient, information, services and real access.

Ηλικία, φύλο και ανοσοποιητικό σύστημα τα στοιχεία που αυξάνουν τον κίνδυνο θανάτου από covid19

Cancer Immunotherapy: A Revolution That Continues to Transform Cancer Care

Over the past fifteen years, cancer immunotherapy has transformed the landscape of oncology, offering new hope and treatment possibilities to patients around the world. What began as a promising scientific concept has evolved into one of the most important pillars of modern cancer treatment.

According to the Cancer Immunotherapy Insights & Impact Report 2026 published by the Cancer Research Institute, a total of 156 immunotherapy approvals were granted by the U.S. Food and Drug Administration (FDA) between 2011 and 2025, reflecting the remarkable growth and impact of this field. Many of these therapies are based on immune checkpoint inhibitors, which help the immune system recognize and attack cancer cells more effectively.

Unlike traditional treatments such as chemotherapy and radiation therapy, immunotherapy works by empowering the body’s own immune system to fight cancer. By enhancing natural immune responses, these therapies can help the body identify and destroy cancer cells that might otherwise evade detection. For many patients, immunotherapy has led to longer survival, improved disease control, and a better quality of life.

The year 2025 marked another milestone in the advancement of cancer immunotherapy, with thirteen new FDA approvals. Notably, patients with anal cancer gained access to their first approved immunotherapy option, highlighting the expanding reach of these innovative treatments. New methods of administration, including subcutaneous therapies, are also making treatment more convenient and accessible for patients.

Research in cancer immunotherapy continues to progress at an extraordinary pace. Scientists are developing new strategies to overcome the mechanisms that allow cancer to hide from the immune system, while exploring novel therapeutic targets, combination treatments, and personalized approaches to care. These advances aim to increase the number of patients who can benefit from immunotherapy and improve outcomes across a wider range of cancers.

While challenges remain and not all patients respond equally to treatment, immunotherapy represents one of the most significant breakthroughs in the history of cancer care. Ongoing scientific innovation continues to bring hope that more effective, personalized, and accessible treatments will become available in the years ahead.

At KAPA3, we recognize the importance of raising awareness about advances in cancer treatment and supporting informed decision-making. Knowledge empowers patients, families, caregivers, and healthcare professionals, helping them navigate the cancer journey with greater confidence and hope.

Source: https://www.cancerresearch.org/cancer-immunotherapy-report-2026

 

Research studies giving voice to lived experience

At Kapa3, we actively encourage participation in health research studies, as we work every day alongside people affected by cancer, whether as patients or caregivers. Through this work, it becomes increasingly clear how important it is to truly listen to lived experience.

For this reason, the research initiatives we support or contribute to are not just questionnaires. They are a way to better understand the needs, experiences and priorities of the community we serve.

Through participation in these studies, individuals who are at the centre of the cancer experience are given the opportunity to share their reality. Every response, every story, every contribution adds another piece to a broader picture: a more meaningful and human-centred approach to care and support.

The contribution of each participant is highly valuable. The data collected helps us identify needs that are often not visible, better understand challenges, and design actions that reflect the real everyday lives of people.

Through participation in health research studies, lived experience can be transformed into knowledge that makes a real difference. Each study we support is part of a broader effort to understand the experiences of patients and caregivers.

Below you will find the current research studies open for participation, organised by target audience.

Each health research study includes a short description of its purpose and how participation contributes to the overall research effort.

For healthcare professionals

Patient safety culture in hospitals

A pilot study focused on the translation and adaptation of the international SOPS® Hospital Survey 2.0 developed by the AHRQ, adapted for the Greek hospital setting.

The aim of the study is to evaluate the clarity, comprehension and suitability of the tool through the participation of healthcare professionals working in hospital environments.

The study also includes a test–retest phase to assess the stability of responses over time.

Participation: https://forms.gle/Jev7mQ95vt1swtXF7

For research networks and collaborations

sleepCare – sleep quality assessment

The sleepCare research initiative, in collaboration with Christos Frantzidis (University of Lincoln) and his research team, explores sleep quality through real-life experiences and self-reported data from participants.

The aim is to better understand the factors that influence sleep in everyday life through anonymous data collection and short questionnaires.

English questionnaire: https://lnkd.in/e7wYjspX
Greek questionnaire: https://lnkd.in/ejbjGQPC
Platform: https://lnkd.in/e7YHUXdi

For breast cancer survivors

Survivorship experience and quality of life

A thesis-based research study examining fear of cancer recurrence, quality of life, and the role of social support among breast cancer survivors in Greece.

The aim is to better understand post-treatment experiences and the factors that influence psychosocial well-being.

Participation: https://docs.google.com/forms/d/e/1FAIpQLSeUgku0yi7LBGg42v_FeKtzVsj5F5uw8hYr-y-hcVKL-fhoeQ/viewform

For patients with respiratory conditions and caregivers

Lung transplantation experiences in Greece

A nationwide study collecting experiences, needs and perspectives of patients with respiratory conditions and their caregivers regarding lung transplantation.

The aim is to capture lived experience across all stages of the disease in order to improve care pathways and healthcare services.

The study is open to patients with respiratory conditions (transplanted or not) as well as their caregivers.

Participation: https://forms.gle/66h4CQJK3pdr1gKK7
Information: https://www.cysticfibrosis.gr/draseis/lung-transplant-working-group/

Text/Adaptation: Ifiyenia Anastasiou for Kapa3