Evangeli Bista Joins the PATH Expert Group as an Independent Expert: Bringing the Patient Perspective into the New Era of AI in Cancer Care

A new contribution to the European dialogue on safe, responsible and human-centred Artificial Intelligence in healthcare

Evangeli Bista, Co-founder and Head of Operations and Development of Kapa3 – Cancer Guidance Centre, has been invited to join the Expert Group of the European research and innovation project PATH – Patient AI Treatment Hub as an independent expert.

Her participation is undertaken in a personal and independent capacity, with her professional affiliation to Kapa3 – Cancer Guidance Centre, creating an opportunity to bring into the European dialogue experience gained through direct engagement with people affected by cancer, survivors, caregivers and healthcare professionals. The PATH Terms explicitly define Expert Group members as acting independently rather than as partners, employees, agents or subcontractors of the Consortium.

What is PATH – Patient AI Treatment Hub?

PATH – Patient AI Treatment Hub is a European research and innovation project focused on supporting the safe and effective integration of Artificial Intelligence into cancer care through the development of a secure, interoperable and privacy-preserving digital platform.

The project aims to explore how Artificial Intelligence tools can be safely integrated into cancer-care pathways, supporting healthcare professionals and contributing to more personalised approaches while safeguarding privacy and health data.

At the heart of this effort lies a critical question:

How can technological innovation create meaningful value for patients while preserving trust, human oversight, safety and equity?

Participation in the PATH Expert Group

As a member of the PATH Expert Group, Evangeli Bista will contribute independent expertise, opinions, input, comments and feedback in relation to selected project use cases and activities.

The experience developed through Kapa3’s work can contribute to discussions around issues such as:

  • patient-centred cancer care,
  • patient navigation across health and social-care systems,
  • equitable access to information and services,
  • health and digital literacy,
  • health and social rights,
  • responsible use and protection of health data,
  • transparency and human oversight in Artificial Intelligence systems,
  • meaningful involvement of patients and civil society in technology design,
  • and translating technological innovation into real value for people.

Why the Patient Voice Must Be Part of Innovation

Artificial Intelligence is creating new possibilities for healthcare and cancer care. At the same time, its growing use raises important questions concerning trust, transparency, safety, equitable access and human oversight.

For Kapa3, the development of a digital solution cannot begin solely with the question of what is technologically possible.

It must also ask:

What does the patient actually need?

Can people understand the information they receive?

Do they know where that information comes from?

Can they trust the system?

Is it clear when Artificial Intelligence is being used and when human professional judgement is required?

Could digital inequalities lead to new inequalities in healthcare?

And ultimately, does innovation genuinely improve the experience and pathway of a person facing cancer?

These are questions that we believe should remain at the centre of the European discussion on Artificial Intelligence in healthcare.

Kapa3’s experience in digital health

Evangeli Bista’s participation in the PATH Expert Group comes at a time when Kapa3 is systematically expanding its work in digital health, patient navigation and the responsible use of emerging technologies to support people affected by cancer.

This broader work also includes MYRTO – Digital Navigator for Health and Social Rights, an independent Kapa3 initiative developed to help transform complex and often fragmented information on rights, benefits and administrative procedures into more accessible, structured and evidence-based guidance for patients and caregivers.

MYRTO is not part of PATH, and the two initiatives are independent from one another.

However, the experience of developing patient-facing digital services has reinforced several principles that Kapa3 considers essential:

reliable information, transparent sources, understandable communication, data protection, human oversight and a clear pathway to professional support when technology alone is not enough.

This distinction is also important from an intellectual-property perspective, since the PATH Terms preserve intellectual property that exists independently of the Expert’s Services and is not incorporated into PATH Contributions.

From information to trust

Digital transformation in healthcare is not simply about more data, more algorithms or more applications.

It is about creating greater understanding, better access and stronger trust.

For a person facing cancer, information has value when it can be translated into a meaningful next step.

Technology has value when it reduces — rather than increases — complexity.

And Artificial Intelligence has value when it strengthens, rather than replaces, human care, professional judgement and the patient’s ability to participate meaningfully in decisions affecting their life and health.

A new opportunity to contribute to the European dialogue

For Kapa3, the invitation to Evangeli Bista to participate as an independent expert in the PATH Expert Group represents an important opportunity to bring into the European dialogue experience, needs and concerns emerging from the real-world context of cancer care and patient support.

The objective remains clear:

Artificial Intelligence in healthcare should advance with safety, transparency, responsibility, equitable access and meaningful involvement of the people it is designed to serve.

Because innovation creates real value when it is designed with people and for people.


PATH – Patient AI Treatment Hub | At a glance

Field: Artificial Intelligence and data in cancer care
Project: PATH – Patient AI Treatment Hub
Focus: Safe and effective integration of AI into cancer care through secure, interoperable and privacy-preserving approaches.
Expert Group: Independent external experts providing expertise, opinions, input, comments and feedback to the Project.
Independent Expert: Evangeli Bista
Professional role: Co-founder & Head of Operations and Development
Affiliation: Kapa3 – Cancer Guidance Centre

 

When Art Meets Science: How CREATE Platform May Strengthen Emotional Regulation in Cancer Care

At Kapa3, we recognize that cancer affects far more than the body, challenging the emotions, sense of self, relationships, and quality of life of those suffering. Despite the high prevalence of co-occuring mental health issues such as anxiety and depression, access to mental health services remains limited. This gap between patient needs and healthcare provisions is precisely what motivated us to help develop CREATE, an innovative digital platform designed to support emotional resilience through a powerful combination of art, technology, and emotional engagement (Ladas et al., 2025).

The CREATE (Creative and Resilience through Arts, Technology, and Emotions) platform uses computerised cognitive training (CCT) designed to enhance emotional regulation by integrating working memory training, engagement with famous artwork, and creative emotional expression. Unlike other platforms, it only targets one cognitive function: working memory. Evidence suggests that focusing on a single cognitive function is more effective than targeting multiple ones. Working memory in particular has been found to influence emotional regulation, a skillset with established benefits for anxiety and depression.

CREATE therefore introduces a unified framework that addresses cognitive function, emotional expression, and biological influences such as sleep quality and dopamine activity. Such digital health solutions are increasingly recognized as promising alternatives to standard psychotherapy, offering greater accessibility and affordability while still capable of reducing symptoms of depression and anxiety.

Findings from the pilot study on CREATE were very promising; the participants found the platform easy to use and enjoyable, and showed increased emotional and creative engagement. Although this early research focused on feasibility and validity rather than therapeutic effectiveness, initial findings indicate improvements in emotional regulation. Importantly, the study demonstrated positive relationships between working memory, emotional regulation, and expression of emotion, while also suggesting that sleep and dopamine may mediate these effects.

These insights highlight the importance of lifestyle and biological data in developing personalized digital mental health tools. It is well established in neuroscience that working memory plays a central role in emotional regulation. A stronger working memory allows individuals to better cope with distressing thoughts, shift their attention, and respond more calmly to challenges. For people living with cancer, supporting these cognitive and emotional capacities makes daily life more manageable. Improved thinking skills can facilitate treatment adherence, informed decision-making, and a more effective management of the emotional turbulence that often accompanies illness.

The study relied on a convenience sample made up mostly of cancer-related healthcare professionals, and only one cancer survivor participated. To address this limitation, the next phase of research will focus entirely on cancer patients and survivors. Their unique challenges, including cancer-related fatigue and treatment-related cognitive changes, will be central to refining the platform and ensuring that CREATE is tailored to the needs of those it aims to benefit the most. This creates not only a more impactful intervention but also empowers patients to have a voice in shaping the future of supportive cancer care.

As we look ahead, CREATE offers a hopeful vision for digital mental-health support. It is scalable, affordable, and adaptable, making it especially valuable for people who lack access to mental health care. Intervening early and supporting emotional well-being throughout treatment and survivorship may reduce the long-term strain on healthcare services associated with mental health conditions.  As cancer treatment continues to evolve, we must make sure that psychological care develops along with it. And CREATE does just that.

Read the full study

References

Ladas, A. I., Katsoridou, C., Gravalas, T., Klados, M. A., Stravoravdi, A. S., Tsompanidou, N., Fragkedaki, A., Bista, E., Chorafa, T., Petrovic, K., Vlotinou, P., Tsiakiri, A., Papazisis, G., & Frantzidis, C. A. (2025). Creativity and REsilience Through Arts, Technology and Emotions: A Pilot Study on the Feasibility and Validity of the CREATE Platform. Brain Sciences, 15(11), 1171.

‌Article by Despina Chrysostomidou, Psychologist, for Kapa3 Research Insights